Promethazine hydrochloride ( Diprazin; Fellozine; Lergigan; Phenergan; Romergan )

Catalog No. M15142 CAS No. 58-33-3

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Product Name

Promethazine hydrochloride
Note

Research use only, not for human use.
Brief Description

Promethazine Hcl(NSC-231688) is the first-generation antihistamine.
Description

Promethazine Hcl(NSC-231688) is the first-generation antihistamine; strong antagonist of the H1 receptor and moderate mACh receptor antagonist, moderate affinity for 5-HT2A, 5-HT2C, D2 and α1-adrenergic receptors.
Synonyms

Diprazin; Fellozine; Lergigan; Phenergan; Romergan
Pathway

Endocrinology/Hormones
Target

Adrenergic Receptor
Recptor

α-adrenergic receptor; H1 receptor
Research Area

Neurological Disease
Indication

——

CAS Number

58-33-3
Formula Weight

320.88
Molecular Formula

C17H20N2S·HCl
Purity

>98%(HPLC)
Solubility

Ethanol: 34 mg/mL (105.95 mM); Water: 64 mg/mL (199.45 mM); DMSO: 64 mg/mL (199.45 mM)
SMILES

Cl.CC(CN1C2=CC=CC=C2SC2=CC=CC=C12)N(C)C
Chemical Name

——

1. Smith BN, Armstrong WE. Neuroscience. 1993 Apr;53(3):855-64.

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